Can Mucuna Pruriens Cause Anxiety?

Written by Ben Bunting: BA, PGCert. (Sport & Exercise Nutrition) // British Army Physical Training Instructor // S&C Coach.


Mucuna pruriens, also known as velvet bean or cowhage, is a plant that’s been used for years in tropical regions for its medicinal benefits.

It’s most commonly used to treat Parkinson’s disease and nervous disorders, but it’s also believed to improve male fertility.

It contains L-dopa, a precursor of dopamine that increases motivation and reduces stress levels. It may even boost testosterone and growth hormone in men.

Itching sensations

Mucuna pruriens is a tropical legume (the botanical name is Stizolobium pruriens) that grows wild in many parts of the world. Its spicules, pods and leaves cause itching sensations in humans when applied to the skin.

The itch sensation is caused by a combination of chemical, electrical, mechanical and thermal stimulation.

The brain receives impulses from these stimuli through the spinal cord. The free nerve endings in C-fibers close to the dermo-epidermal junction send impulses down the spinal cord and into the somatosensory cortex of the postcentral gyrus.

Researchers have found that heating the skin increases itch sensations. They think this may be related to the effects of thermoception and pruriception.

They also think that itching sensations are mediated by the amygdala. While it is common for this brain region to be activated in response to pain, a recent study has shown that it is also associated with itch sensations.

Itching is thought to be elicited by a protein called mucunain, which is present in the spicules of M. pruriens.

Mucunain is a cysteine protease that causes itching sensations in humans. Its activity is regulated by the activation of TRPV3 channels in keratinocytes. Similarly, papain and histamine elicit itching in mice through their action on the PAR2 receptor.

They were able to isolate and identify the active component of mucunain using a variety of extraction, separation and mass spectrometric techniques.

Short-term memory loss

Mucuna pruriens (also known as the velvet bean) is a plant used for centuries in Ayurvedic medicine for a variety of nervous system conditions, including Parkinson's disease.

Its seed powder is rich in l-dopa, which is a precursor to dopamine. It has also been shown to have anti-oxidant properties, which may help reduce the occurrence of nerve damage caused by illness and stress.

Mucuna pruriens is a climbing legume found in India and other tropical areas around the world. It has a long vine that can reach up to 15 meters. It is covered with fuzzy, white hairs, which can cause itching sensations when touched.

In order to prevent this itching, a special strain of mucuna is grown that has much less of these hairs on the plants.

It is also much more productive than the traditional variety and is cultivated by expert handlers with strict safety measures.

The seeds have also been studied for their neuroprotective effects, which are believed to be due to its anti-oxidant properties.

It has been found to inhibit the neurotoxicity induced by Parkinson's disease in animal models.

In a recent study, researchers compared the clinical effects and pharmacokinetics of a 30g mucuna preparation with standard l-dopa/carbidopa (LD/CD) to see if it could be an effective alternative to L-dopa for patients who have a short l-dopa response but cannot afford to take LD/CD for long periods.

They found that the mucuna formulation consistently induced a sustained on-period of response and produced comparable quality of motor improvement to LD/CD.

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Decreased libido

The legume mucuna pruriens, also called Velvet bean or cowhage, has been used for thousands of years in herbal and Ayurvedic medicine.

It has been known as a potent adaptogen and nutritive tonic, nourishing the nervous system, supporting healthy sexual energy, strengthening and toning the reproductive organs, and improving mood.

It has been a popular remedy for nervous disorders, Parkinson's disease, and male infertility. It is a source of L-dopa, an essential precursor to the neurotransmitter dopamine.

When taken as a supplement, mucuna pruriens increases the amount of dopamine in your body, and can help treat anxiety, improve focus, boost libido, and improve mood. It also lowers stress, improves sleep, and reduces pain.

Mucuna pruriens is also a powerful antiparkinson drug, with antioxidant and metal chelating properties. It is also a popular aphrodisiac that increases sexual desire, treats premature ejaculation, improves sperm quality, and increases testosterone levels.

However, the herb can decrease libido in some people. This is especially true for men with high levels of MAO activity, which breaks down dopamine faster than other people.


A 2019 study looked at the effects of mucuna pruriens as an anti-anxiety treatment. The results indicate that mucuna could be a useful therapy for anxiety. However, this study was based on the animal model. 

Mucuna has also been shown to increase the body’s production of both dopamine and serotonin, which is what may help reduce anxiety symptoms.

This is because dopamine and serotonin are important for controlling our moods, sleep cycles and stress levels.

However, taking mucuna along with other medications can also cause an increased heart rate and pounding sensations in the chest, which can lead to anxiety.

This is because the plant contains a substance called trypsin inhibitor that can disrupt your ability to absorb protein.

In addition to increasing the heart rate, mucuna pruriens can also cause symptoms of psychosis such as confusion, agitation and hallucinations.

This is why it is recommended to take velvet bean with a doctor’s supervision, especially if you are currently taking drugs for depression or other mental health conditions.

Increased blood pressure

Mucuna pruriens, is an bean that can help lower blood pressure. This is because it contains L-dopa, which boosts dopamine levels in the brain. This helps keep you focused and alert.

In addition, it can lower high blood sugar levels and fight anxiety. It also has antioxidant properties, which can reduce inflammation in the body.

The beans of this plant are rich in protein and essential nutrients. They can also provide a wide range of health benefits, including anti-aging and anti-diabetic effects. 

A supplemental form of Mucuna pruriens can lower cholesterol levels, which may help prevent heart disease. It also can help fight fatigue and insomnia. It’s a natural treatment for chronic pain, too.

Mucuna pruriens has also been shown to boost testosterone in males who are struggling with infertility. It also improves the quality of sperm. It’s not clear whether it can improve libido in men, though.

Mucuna pruriens is an herbal tonic that’s often used to treat nervous system disorders, as well as endocrine imbalances.

It’s also a natural source of levodopa, a neurotransmitter that helps your mood. It can be helpful in treating depression, but it’s best to talk to a doctor before you start using it.


Insomnia is a condition that can affect the quality of sleep. It can happen for a variety of reasons, from stress to jet lag to pregnancy.

The sleep you get has a huge impact on your health and well-being. In fact, a lack of quality sleep can increase your risk for several diseases and disorders.

It is important to understand how insomnia can affect you, and what the treatment options are. Most cases of insomnia are treatable by making simple changes to your sleep habits, and addressing the cause of your symptoms.

Getting enough sleep can make all the difference in your mood and overall health. If you're not sleeping properly, it can negatively affect your physical and mental health, and even your work and school performance. 

You can see a therapist who can help you develop a sleep plan for improved sleep hygeine and provide support as you try to sleep more soundly. Insomnia can be treated with a range of strategies, including therapy, medication and lifestyle changes.


This tropical leguma has long been known to have the potential to support a healthy nervous system, libido and reproductive health.

Its velvety seed pods are a natural source of levodopa (L-dopa), an essential precursor to the neurotransmitter dopamine.

It is used in traditional Indian medicine for conditions including Parkinson’s disease.

Mucuna pruriens is a herb that is revered for its uplifting properties. It can help reduce anxiety and stress, increase energy, improve motivation, clear brain fog, boost mood, and promote a sense of calm.

Besides its L-dopa benefits, this plant is also believed to have anti-microbial activity against some bacteria. It has a strong effect on the gastrointestinal tract and can support proper digestion.

The velvet bean’s other important role in the body is its calming effects on the central nervous system.

The herb can help to relieve a wide range of symptoms related to stress and anxiety, such as muscle tension, fatigue, insomnia, poor memory and concentration, and difficulty thinking clearly.

This herb is generally safe for most people at moderate doses. However, it should be avoided if you are taking monoamine oxidase inhibitors (MAOIs), which are commonly used to treat depression.

MAOIs prevent the enzymes in your body from breaking down the neurotransmitters serotonin and norepinephrine, which increases dopamine levels in your brain.

Mucuna pruriens is regarded as a nutritive tonic and adaptogen by Ayurveda, and it has been used to support a healthy nervous system, sexual energy, and healthy reproduction in men.

In addition, it is a powerful neuroprotector, helping to scavenge for free radicals in the brain.

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